Nifedipine lowers blood pressure by relaxing blood vessels. This action reduces the workload on your heart. Remember, always follow your doctor’s instructions precisely.
Dosage and Administration
Your doctor determines the correct dosage based on your individual needs and health status. Typical dosages range from 10mg to 90mg per day, administered in divided doses. Never adjust your dosage without consulting your physician.
Common Side Effects
- Headache
- Dizziness
- Flushing
- Swelling in ankles and feet
These side effects are usually mild and temporary. If they persist or worsen, contact your doctor immediately.
Serious Side Effects (Seek immediate medical attention)
- Chest pain
- Rapid or irregular heartbeat
- Severe dizziness or fainting
- Shortness of breath
This list isn’t exhaustive; report any unusual symptoms to your healthcare provider.
Drug Interactions
Nifedipine can interact with various medications, including some antifungals, antibiotics, and HIV medications. Inform your doctor about all medications, supplements, and herbal remedies you are taking to prevent potential adverse reactions. This includes over-the-counter drugs.
This information is for educational purposes only and does not replace professional medical advice. Always consult your physician or pharmacist for personalized guidance regarding your medication.
Interactions with Other Medications: Important Considerations
Always inform your doctor or pharmacist about all medications you are taking, including over-the-counter drugs, supplements, and herbal remedies. Nifedipine can interact significantly with several drug classes.
Grapefruit Juice and Other Inhibitors
Avoid grapefruit juice and other CYP3A4 inhibitors like ketoconazole, itraconazole, and erythromycin. These substances increase nifedipine levels in your blood, potentially leading to dangerously low blood pressure.
Simvastatin and Other Statins
Concomitant use with certain statins like simvastatin can increase the risk of myopathy (muscle damage). Your doctor may need to adjust your statin dosage or choose an alternative.
Beta-blockers
While not always a contraindication, combining nifedipine with beta-blockers can sometimes cause excessive heart rate slowing or reduced blood pressure. Close monitoring is necessary.
Digoxin
Nifedipine can increase digoxin levels, potentially resulting in toxicity. Regular monitoring of digoxin levels is recommended if you’re taking both medications.
This information is not exhaustive. Discuss any potential drug interactions with your healthcare provider before starting or changing any medications. They can assess your individual risk and adjust your treatment plan accordingly.
